Evolutionary Biology meets the Antibiotic Crisis vol. 2

24 Sept 2024, 13:00 → 26 Sept 2024, 16:00 Europe/Berlin

Tuesday 24 September

13:00 → 13:30 Welcome & Snacks

13:30 → 15:20 Session: 1

Convener: Hildegard Uecker (MPI for Evolutionary Biology)

13:30 Talk Sebastian Bonhoeffer

Speaker: Sebastian Bonhoeffer (ETH Zürich)

14:10 Mathematical models for resistance evolution in multi-drug environments

Speaker: Christin Nyhoegen (FU Berlin)

14:50 Theoretical insights into resistance evolution in non-mixing and mixing transfer protocols

Speaker: Ernesto Berrios-Caro (MPI for Evolutionary Biology)

15:05 Impact of Treatment Strategies on the Epidemiological Dynamics of Horizontally Transferred Antibiotic Resistance

Speaker: Malte Mütter (ETH Zürich)

15:20 → 15:50 Break

15:50 → 17:00 Session: 2

Convener: Ronan Murphy

15:50 Antibiotic tolerance versus resistance evolution: implications for clinical microbiology

Speaker: Annette Moter (Charité)

16:30 Cross-linked agarose-gelatin beads as a substrate for investigating bacterial biofilms

Speaker: Maren Herzog (FU Berlin)

16:45 Infection dynamics in the urinary tract - The importance of non-planktonic phases during early infection and resistance evolution

Speaker: Amanda Azevedo-Lopes (MPI for Evolutionary Biology)

17:00 → 17:15 Break

17:15 → 18:40 Session: 3

Convener: Florian Buchholz

17:15 Predicting the emergence of clinically-relevant antibiotic resistance

Speaker: Nancy Obeng (F. Hoffmann-La Roche LTD)

17:30 Predicting drug resistance to new Mycobacterium tuberculosis drugs before commercial use

Speaker: Lindsay Sonnenkalb (Research Center Borstel)

17:45 Resistance evolution to antimicrobial biocides

Speaker: Frank Schreiber (BAM)

18:00 Antibiotic prophylaxis in the light of AMR emergence

Speaker: Jan Rupp (UKSH)

18:40 → 19:30 Dinner

19:30 → 20:10 Session: 4

Convener: Arne Traulsen

19:30 Staphylococcal In Host Adaption and Evolution

Speaker: Annelies Zinkernagel (Universitätsspital Zürich)

Wednesday 25 September

09:00 → 10:10 Session: 5

Convener: Aditi Batra

09:00 Potential and risk of targeting bacterial iron uptake

Speaker: Rolf Kümmerli (University of Zürich)

09:40 Antimicrobial activity of iron-depriving pyoverdines against human pathogens

Speaker: Vera Vollenweider (University of Zürich)

09:55 Commensal-pathogen interactions as a source for microbiota-targeted treatments

Speaker: Silvio Brugger (University of Zürich)

10:10 → 10:40 Break

10:40 → 12:40 Session: 6

Conveners: Fereshteh Ghazisaeedi, Trisha Parbhoo

10:40 Mechanistic insights into phage antibiotic synergism

Speaker: Frederic Bertels (MPI for Evolutionary Biology)

11:20 Why bacteria-bacteria interactions matter and what can be learned from bacteria-bacteria killing in nature

Speaker: Daniel Unterweger (MPI for Evolutionary Biology, Kiel University)

12:00 Mass lysis of predatory bacteria drives the enrichment of antibiotic resistance in soil microbial communities

Speaker: Samay Pande (Indian Institute of Science)

12:40 → 13:30 Lunch

13:30 → 15:00 Discussion: Group Discussions

15:00 → 15:45 Discussion: Plenary Discussion

15:45 → 16:00 Break

16:00 → 18:20 Session: 7

Convener: Nancy Obeng

16:00 Limiting the spread of resistance on plasmids

Speaker: Hildegard Uecker (MPI for Evolutionary Biology)

16:40 An evolutionary perspective on antibiotic treatment

Speaker: Aditi Batra (Kiel University, MPI for Evolutionary Biology)

16:55 In Vitro Selection vs. In Vivo Adaptation: Unveiling Divergent paths in Antimicrobial Resistance Evolution (Insilco study)

Speaker: Mohammed Elbediwi (FU Berlin)

17:10 Non-canonical antibiotic interactions.

Speaker: Roderich Römhild (IST Austria)

17:25 Evolutionary consequences of variation in mutation rates for antibiotic resistance

Speaker: Florian Buchholz (Kiel University, MPI for Evolutionary Biology)

17:40 The evolution of antibiotic resistance islands in plasmids

Speaker: Tal Dagan (Kiel University)

19:00 → 21:00 Restaurant Dinner

Thursday 26 September

09:00 → 10:40 Session: 8

Convener: Roderich Römhild

09:00 Molecular mechanisms of bacterial heteroresistance

Speaker: Marcus Fulde (FU Berlin)

09:40 De novo evolution of antibiotic heteroresistance under sequential treatment

Speaker: Nan Ye (Kiel University & MPI for Evolutionary Biology)

09:55 From heteroresistance to resistance: role of gene duplication-amplification events in Enterobacter cloacae

Speaker: Johannes Kupke (FU Berlin)

10:10 Understanding the induction of tolerance and persistence under temporally dynamic antimicrobial applications

Speaker: Khairy Mohammed Ali (FU Berlin)

10:25 Antimicrobial Peptides and Cell Age Influence the Emergence of Bacterial Persisters

Speaker: Ronan Murphy (FU Berlin)

10:40 → 11:10 Break

11:10 → 12:45 Session: 9

Convener: Christin Nyhoegen

11:10 Pharmacodynamic functions: their history, their role in predicting resistance evolution, and current frontiers

Speaker: Roland Regoes (ETH Zürich)

11:50 Agent-based Modeling of Antimicrobial Peptide Killing Dynamics

Speaker: Christopher Witzany (ETH Zürich)

12:05 Double the Trouble: Exploring the Complexities of Drug Resistance Evolution in Diploid Organisms

Speaker: Barbora Trubenova (ETH Zürich & EAWAG)

12:45 → 13:40 Lunch

13:40 → 15:00 Session: 10

Convener: Mohammed Elbediwi

13:40 Factors associated with the evolution of anthelmintic resistance in parasitic nematodes and current concepts for its prevention

Speaker: Georg von Samson-Himmelstjerna (FU Berlin)

14:20 What can fermented anthelmintics contribute to gastrointestinal nematode parasite control?

Speaker: Raffi Aroian (University of Massachussetts)

15:00 → 15:20 Offical End and Farewell