Evolutionary Rescue - bridging the gap between theory and experiments

Session

Richard Gomulkiewicz Lecture

30 Jun 2025, 18:30

Max Planck Institute for Evolutionary Biology

5. Feller diffusion approximations for analyzing Luria Delbrück experiments

Guillaume Martin

30/06/2025, 18:30

The Luria Delbrück experiment has 80 years of history and is arguably the most widely used method of analyzing evolutionary rescue (ER) in microbes. It consists in growing replicate, initially clonal, populations in permissive conditions then abruptly switching each replicate onto a petri dish containing selective lethal conditions (eg antibiotics or lytic phages). Finally, the number of...