Evolutionary Biology meets the Antibiotic Crisis vol. 2

24 Sept 2024, 13:00 → 26 Sept 2024, 16:00 Europe/Berlin

Tuesday 24 September

13:00 Welcome & Snacks

Session: 1

Convener: Hildegard Uecker (MPI for Evolutionary Biology)

1 Talk Sebastian Bonhoeffer

Speaker: Sebastian Bonhoeffer (ETH Zürich)

2 Mathematical models for resistance evolution in multi-drug environments

Speaker: Christin Nyhoegen (FU Berlin)

3 Theoretical insights into resistance evolution in non-mixing and mixing transfer protocols

Speaker: Ernesto Berrios-Caro (MPI for Evolutionary Biology)

4 Impact of Treatment Strategies on the Epidemiological Dynamics of Horizontally Transferred Antibiotic Resistance

Speaker: Malte Mütter (ETH Zürich)

15:20 Break

Session: 2

Convener: Ronan Murphy

5 Antibiotic tolerance versus resistance evolution: implications for clinical microbiology

Speaker: Annette Moter (Charité)

6 Cross-linked agarose-gelatin beads as a substrate for investigating bacterial biofilms

Speaker: Maren Herzog (FU Berlin)

7 Infection dynamics in the urinary tract - The importance of non-planktonic phases during early infection and resistance evolution

Speaker: Amanda Azevedo-Lopes (MPI for Evolutionary Biology)

17:00 Break

Session: 3

Convener: Florian Buchholz

8 Predicting the emergence of clinically-relevant antibiotic resistance

Speaker: Nancy Obeng (F. Hoffmann-La Roche LTD)

9 Predicting drug resistance to new Mycobacterium tuberculosis drugs before commercial use

Speaker: Lindsay Sonnenkalb (Research Center Borstel)

10 Resistance evolution to antimicrobial biocides

Speaker: Frank Schreiber (BAM)

11 Antibiotic prophylaxis in the light of AMR emergence

Speaker: Jan Rupp (UKSH)

18:40 Dinner

Session: 4

Convener: Arne Traulsen

12 Staphylococcal In Host Adaption and Evolution

Speaker: Annelies Zinkernagel (Universitätsspital Zürich)

Wednesday 25 September

Session: 5

Convener: Aditi Batra

13 Potential and risk of targeting bacterial iron uptake

Speaker: Rolf Kümmerli (University of Zürich)

14 Antimicrobial activity of iron-depriving pyoverdines against human pathogens

Speaker: Vera Vollenweider (University of Zürich)

15 Commensal-pathogen interactions as a source for microbiota-targeted treatments

Speaker: Silvio Brugger (University of Zürich)

10:10 Break

Session: 6

Conveners: Fereshteh Ghazisaeedi, Trisha Parbhoo

16 Mechanistic insights into phage antibiotic synergism

Speaker: Frederic Bertels (MPI for Evolutionary Biology)

17 Why bacteria-bacteria interactions matter and what can be learned from bacteria-bacteria killing in nature

Speaker: Daniel Unterweger (MPI for Evolutionary Biology, Kiel University)

18 Mass lysis of predatory bacteria drives the enrichment of antibiotic resistance in soil microbial communities

Speaker: Samay Pande (Indian Institute of Science)

12:40 Lunch

Discussion: Group Discussions

Discussion: Plenary Discussion

15:45 Break

Session: 7

Convener: Nancy Obeng

19 Limiting the spread of resistance on plasmids

Speaker: Hildegard Uecker (MPI for Evolutionary Biology)

20 An evolutionary perspective on antibiotic treatment

Speaker: Aditi Batra (Kiel University, MPI for Evolutionary Biology)

21 In Vitro Selection vs. In Vivo Adaptation: Unveiling Divergent paths in Antimicrobial Resistance Evolution (Insilco study)

Speaker: Mohammed Elbediwi (FU Berlin)

22 Non-canonical antibiotic interactions.

Speaker: Roderich Römhild (IST Austria)

23 Evolutionary consequences of variation in mutation rates for antibiotic resistance

Speaker: Florian Buchholz (Kiel University, MPI for Evolutionary Biology)

24 The evolution of antibiotic resistance islands in plasmids

Speaker: Tal Dagan (Kiel University)

19:00 Restaurant Dinner

Thursday 26 September

Session: 8

Convener: Roderich Römhild

25 Molecular mechanisms of bacterial heteroresistance

Speaker: Marcus Fulde (FU Berlin)

26 De novo evolution of antibiotic heteroresistance under sequential treatment

Speaker: Nan Ye (Kiel University & MPI for Evolutionary Biology)

27 From heteroresistance to resistance: role of gene duplication-amplification events in Enterobacter cloacae

Speaker: Johannes Kupke (FU Berlin)

28 Understanding the induction of tolerance and persistence under temporally dynamic antimicrobial applications

Speaker: Khairy Mohammed Ali (FU Berlin)

29 Antimicrobial Peptides and Cell Age Influence the Emergence of Bacterial Persisters

Speaker: Ronan Murphy (FU Berlin)

10:40 Break

Session: 9

Convener: Christin Nyhoegen

30 Pharmacodynamic functions: their history, their role in predicting resistance evolution, and current frontiers

Speaker: Roland Regoes (ETH Zürich)

31 Agent-based Modeling of Antimicrobial Peptide Killing Dynamics

Speaker: Christopher Witzany (ETH Zürich)

32 Double the Trouble: Exploring the Complexities of Drug Resistance Evolution in Diploid Organisms

Speaker: Barbora Trubenova (ETH Zürich & EAWAG)

12:45 Lunch

Session: 10

Convener: Mohammed Elbediwi

33 Factors associated with the evolution of anthelmintic resistance in parasitic nematodes and current concepts for its prevention

Speaker: Georg von Samson-Himmelstjerna (FU Berlin)

34 What can fermented anthelmintics contribute to gastrointestinal nematode parasite control?

Speaker: Raffi Aroian (University of Massachussetts)

15:00 Offical End and Farewell