Modeling Diversity in Cancer And Virus Evolution

from Monday, 14 May 2018 (12:00) to Thursday, 17 May 2018 (14:00)
MPI for Evolutionary Biology (Lecture Hall)

        : Sessions
    /     : Talks
        : Breaks
14 May 2018
15 May 2018
16 May 2018
17 May 2018
AM
09:00
Session 1 (until 10:30) (Lecture Hall)
09:00 The evolutionary history of colorectal cancers - Ian Tomlinson   (Lecture Hall)
09:50 Learning and perturbing the evolutionary mechanisms driving therapeutic resistance in cancer - Jacob Scott   (Lecture Hall)
10:30 --- Coffee Break ---
11:00
Session 2 (until 12:30) (Lecture Hall)
11:00 Personalized adaptive therapies for metastatic melanoma: A phase I approach - Alexander R. A. Anderson   (Lecture Hall)
11:50 Inferring clonal mutations from a spatial computational model of intratumour heterogeneity - Luka Opasic   (Lecture Hall)
12:10 Experimental and Mathematical Modelling of Collateral Sensitivity in Heterogeneous Cancer Populations - Daniel Nichol   (Lecture Hall)
09:00
Session 5 (until 10:30) (Lecture Hall)
09:00 Estimating the mutational fitness effects distribution during early HIV infection - Roland Regös   (Lecture Hall)
09:50 Detection of Immune-mediated negative selection using dN/dS - Luis Zapata   (Lecture Hall)
10:10 Pathways to resistance in growing populations over fitness valleys - Michael Nicholson   (Lecture Hall)
10:30 --- Coffee Break ---
11:00
Session 6 (until 12:10) (Lecture Hall)
11:00 Measuring evolutionary dynamics of human cancers from genomic data - Trevor Graham   (Lecture Hall)
11:50 Stopping treatment of CML in virtual patients - Marvin Böttcher   (Lecture Hall)
09:00
Session 8 (until 10:30) (Lecture Hall)
09:00 Keynote: Tibor Antal - Tibor Antal   (Lecture Hall)
09:50 Discussion: What can cancer evolution learn from virus dynamics? What can virus evolution learn from cancer dynamics?   (Lecture Hall)
10:30 --- Coffee Break ---
11:00
Session 9 (until 12:00) (Lecture Hall)
11:00 The dynamics of adaptive genetic diversity during the early stages of clonal evolution - Jamie Blundell   (Lecture Hall)
11:20 How do cellular selection and diversity contribute to leukemic progression? Seeking answers using computational and mathematical analyses - Philipp Altrock   (Lecture Hall)
PM
16:45
Welcome & Evening Lecture (until 17:00) (Lecture Hall)
17:00
Welcome & Evening Lecture (until 18:00) (Lecture Hall)
18:00 --- Get Together ---
12:30 --- Lunch Break ---
14:00
Session 3 (until 15:20) (Lecture Hall)
14:00 Evolution of Competing Diversities: Tumor vs. Immune - Mark Robertson-Tessi   (Lecture Hall)
14:20 A roadmap to precision medicine in breast cancer bone metastases - Sanjay Tiwari   (Lecture Hall)
14:40 Evolution of resistance to ALK targeting therapies in NSCLC - Andriy Marusyk   (Lecture Hall)
15:20 --- Coffee Break ---
15:50
Session 4 (until 17:25) (Lecture Hall)
15:50 Convergence in viral populations - Frederic Bertels   (Lecture Hall)
16:30 Exploring evolutionary trajectories of populations subjected to sequences of drugs in vitro - Nikhil Krishnan   (Lecture Hall)
16:55 In-depth characterization of a hallmark for balancing selection: HLA heterozygote advantage against HIV-1 - Jatin Arora   (Lecture Hall)
18:00 --- Dinner ---
19:00
Afterwards: Discussions (until 20:00) (Lecture Hall)
12:10 --- Lunch Break ---
13:40
Session 7 (until 15:10) (Lecture Hall)
13:40 Evolution of Clonal Heterogeneity in Chronic Myelomonocytic Leukemia - Meghan Ferrall-Fairbanks   (Lecture Hall)
14:20 Immunogenicity and tumor dormancy in brain metastases: comparison of central and peripheral markers of tumor dormancy in relation to NKG2DL expression - Charlotte Flueh   (Lecture Hall)
14:45 Front dynamics and evolution associated with spatial spread - Wolfram Moebius   (Lecture Hall)
15:30 --- Optional: Tour of the institute ---
16:15 --- Boat Trip, Dinner & Discussions ---
18:15 --- Discussion: What can cancer evolution learn from virus dynamics? What can virus evolution learn from cancer dynamics? ---
12:00 Farewell - Philipp Altrock Arne Traulsen   (Lecture Hall)